Mutational Analysis of Rab3 Function for Controlling Active Zone Protein Composition at the Drosophila Neuromuscular Junction

Shirui Chen; Hannah K. Gendelman; John P. Roche; Peter Alsharif; Ethan R. Graf

doi:10.1371/journal.pone.0136938

Loading metrics

Open Access

Peer-reviewed

Research Article

Mutational Analysis of Rab3 Function for Controlling Active Zone Protein Composition at the Drosophila Neuromuscular Junction

Shirui Chen ,

Contributed equally to this work with: Shirui Chen, Hannah K. Gendelman

Affiliation Department of Biology, Amherst College, Amherst, Massachusetts, United States of America
⨯
Hannah K. Gendelman ,

Contributed equally to this work with: Shirui Chen, Hannah K. Gendelman

Affiliation Department of Biology, Amherst College, Amherst, Massachusetts, United States of America
⨯
John P. Roche,

Affiliation Department of Biology, Amherst College, Amherst, Massachusetts, United States of America
⨯
Peter Alsharif,

Affiliation Department of Biology, Amherst College, Amherst, Massachusetts, United States of America
⨯
Ethan R. Graf

* E-mail: egraf@amherst.edu

Affiliation Department of Biology, Amherst College, Amherst, Massachusetts, United States of America
⨯

Mutational Analysis of Rab3 Function for Controlling Active Zone Protein Composition at the Drosophila Neuromuscular Junction

Shirui Chen,
Hannah K. Gendelman,
John P. Roche,
Peter Alsharif,
Ethan R. Graf

Published: August 28, 2015
https://doi.org/10.1371/journal.pone.0136938

About the Authors

Shirui Chen

Contributed equally to this work with: Shirui Chen, Hannah K. Gendelman

Affiliation Department of Biology, Amherst College, Amherst, Massachusetts, United States of America

Hannah K. Gendelman

Contributed equally to this work with: Shirui Chen, Hannah K. Gendelman

Affiliation Department of Biology, Amherst College, Amherst, Massachusetts, United States of America

John P. Roche

Affiliation Department of Biology, Amherst College, Amherst, Massachusetts, United States of America

Peter Alsharif

Affiliation Department of Biology, Amherst College, Amherst, Massachusetts, United States of America

Ethan R. Graf

* E-mail: egraf@amherst.edu

Affiliation Department of Biology, Amherst College, Amherst, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SC HKG JPR ERG. Performed the experiments: SC HKG JPR PA ERG. Analyzed the data: SC HKG JPR PA ERG. Contributed reagents/materials/analysis tools: SC HKG PA ERG. Wrote the paper: JPR ERG.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Vesicles
Is the Subject Area "Vesicles" applicable to this article?

Thanks for your feedback.
Drosophila melanogaster
Is the Subject Area "Drosophila melanogaster" applicable to this article?

Thanks for your feedback.
Phenotypes
Is the Subject Area "Phenotypes" applicable to this article?

Thanks for your feedback.
Synaptic vesicles
Is the Subject Area "Synaptic vesicles" applicable to this article?

Thanks for your feedback.
Neurons
Is the Subject Area "Neurons" applicable to this article?

Thanks for your feedback.
Larvae
Is the Subject Area "Larvae" applicable to this article?

Thanks for your feedback.
Axonal transport
Is the Subject Area "Axonal transport" applicable to this article?

Thanks for your feedback.
Synapses
Is the Subject Area "Synapses" applicable to this article?

Thanks for your feedback.