About the Authors

Mizuki Takemoto

Contributed equally to this work with: Mizuki Takemoto, Hideaki E. Kato, Michio Koyama

Affiliation Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113–0033, Japan

Hideaki E. Kato

Contributed equally to this work with: Mizuki Takemoto, Hideaki E. Kato, Michio Koyama

Current address: Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, California 94305, United States of America

Affiliation Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113–0033, Japan

Michio Koyama

Contributed equally to this work with: Mizuki Takemoto, Hideaki E. Kato, Michio Koyama

Affiliation Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113–0033, Japan

Jumpei Ito

Affiliation Department of Bioengineering Sciences, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464–8601, Japan

Motoshi Kamiya

Affiliation Department of Chemistry, Graduate School of Science, Kyoto University, Kyoto 606–8502, Japan

Shigehiko Hayashi

Affiliation Department of Chemistry, Graduate School of Science, Kyoto University, Kyoto 606–8502, Japan

Andrés D. Maturana

Affiliation Department of Bioengineering Sciences, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464–8601, Japan

Karl Deisseroth

Affiliation Department of Bioengineering and Howard Hughes Medical Institute, Stanford University, Stanford, California 94305, United States of America

Ryuichiro Ishitani

nureki@bs.s.u-tokyo.ac.jp (ON); ishitani@bs.s.u-tokyo.ac.jp (RI)

Affiliation Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113–0033, Japan

Osamu Nureki

nureki@bs.s.u-tokyo.ac.jp (ON); ishitani@bs.s.u-tokyo.ac.jp (RI)

Affiliation Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113–0033, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MT RI ON. Performed the experiments: MT M. Koyama M. Kamiya HEK JI ADM. Analyzed the data: MT M. Koyama HEK RI. Contributed reagents/materials/analysis tools: M. Kamiya SH. Wrote the paper: MT HEK SH RI KD ON.