Analgesic Effect of Electroacupuncture in a Mouse Fibromyalgia Model: Roles of TRPV1, TRPV4, and pERK

Jaung-Geng Lin; Ching-Liang Hsieh; Yi-Wen Lin

doi:10.1371/journal.pone.0128037

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Open Access

Peer-reviewed

Research Article

Analgesic Effect of Electroacupuncture in a Mouse Fibromyalgia Model: Roles of TRPV1, TRPV4, and pERK

Jaung-Geng Lin,

Affiliation College of Chinese Medicine, School of Chinese Medicine, China Medical University, Taichung 40402, Taiwan
⨯
Ching-Liang Hsieh,

Affiliations College of Chinese Medicine, Graduate Institute of Integrative Medicine, China Medical University, Taichung 40402, Taiwan, China Medical University Hospital, Department of Chinese Medicine, Taichung, 40402, Taiwan, Research Center for Chinese Medicine & Acupuncture, China Medical University, Taichung 40402, Taiwan
⨯
Yi-Wen Lin

* E-mail: yiwenlin@mail.cmu.edu.tw

Affiliations Research Center for Chinese Medicine & Acupuncture, China Medical University, Taichung 40402, Taiwan, College of Chinese Medicine, Graduate Institute of Acupuncture Science, China Medical University, Taichung 40402, Taiwan
⨯

Analgesic Effect of Electroacupuncture in a Mouse Fibromyalgia Model: Roles of TRPV1, TRPV4, and pERK

Jaung-Geng Lin,
Ching-Liang Hsieh,
Yi-Wen Lin

Published: June 4, 2015
https://doi.org/10.1371/journal.pone.0128037

About the Authors

Jaung-Geng Lin

Affiliation College of Chinese Medicine, School of Chinese Medicine, China Medical University, Taichung 40402, Taiwan

Ching-Liang Hsieh

Affiliations College of Chinese Medicine, Graduate Institute of Integrative Medicine, China Medical University, Taichung 40402, Taiwan, China Medical University Hospital, Department of Chinese Medicine, Taichung, 40402, Taiwan, Research Center for Chinese Medicine & Acupuncture, China Medical University, Taichung 40402, Taiwan

Yi-Wen Lin

* E-mail: yiwenlin@mail.cmu.edu.tw

Affiliations Research Center for Chinese Medicine & Acupuncture, China Medical University, Taichung 40402, Taiwan, College of Chinese Medicine, Graduate Institute of Acupuncture Science, China Medical University, Taichung 40402, Taiwan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JGL CLH YWL. Performed the experiments: YWL. Analyzed the data: CLH YWL. Contributed reagents/materials/analysis tools: JGL YWL. Wrote the paper: JGL CLH YWL.

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Fibromyalgia
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Hyperalgesia
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Neurons
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Mouse models
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Pain
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Intramuscular injections
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Sensory perception
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Inflammation
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