About the Authors

Gabriela Ispas

gispas@its.jnj.com

Affiliation Janssen Infectious Diseases, Beerse, Belgium

Anil Koul

Affiliation Janssen Infectious Diseases, Beerse, Belgium

Johan Verbeeck

Affiliation Janssen Research & Development, London, United Kingdom

Jennifer Sheehan

Affiliation Huntingdon Life Sciences, 100 Mettlers Road, Somerset, NJ 08873, United States of America

Brigitte Sanders-Beer

Affiliation BIOQUAL, Inc., 9600 Medical Center Drive, Rockville, MD 20850, United States of America

Dirk Roymans

Affiliation Janssen Infectious Diseases, Beerse, Belgium

Koen Andries

Affiliation Janssen Infectious Diseases, Beerse, Belgium

Marie-Claude Rouan

Affiliation Janssen Research & Development, Beerse, Belgium

Sandra De Jonghe

Affiliation Janssen Research & Development, Beerse, Belgium

Jean-François Bonfanti

Affiliation Jan-Cil France, Janssen Research & Development, Paris, French Republic

Marc Vanstockem

Affiliation Janssen Infectious Diseases, Beerse, Belgium

Kenneth Simmen

Affiliation Jan-Cil UK, J&J Pharmaceutical Research & Development, High Wycombe, United Kingdom

Rene Verloes

Affiliation Janssen Infectious Diseases, Beerse, Belgium

Competing Interests

Gabriela Ispas, Anil Koul, Johan Verbeeck, Dirk Roymans, Koen Andries, Marie-Claude Rouan, Jean-François Bonfanti, MarcVanstockem, Kenneth Simmen, Rene Verloes are employees of companies within Janssen Pharmaceutical Companies of J&J, ie: Janssen Infectious Disease, Janssen R&D, Tibotec BVBA, Jan-Cil France, Jan-Cil UK. Anil Koul, Johan Verbeeck, Koen Andries, MarcVanstockem, Kenneth Simmen and Rene Verloes hold stocks in the company. Jennifer Sheehan is employee of Huntington Life Sciences and Brigitte Sanders-Beer is employee of Bioqual. All authors confirm that this does not alter their adherence to all PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AK DR KA MCR JFB RV. Performed the experiments: JV JS BSB. Analyzed the data: GI SDJ MV KS. Contributed reagents/materials/analysis tools: JV JS BSB. Wrote the paper: GI AK.