About the Authors

Hasan Arrat

Affiliation Department of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, IL, 60611, United States of America

Thomas J. Lukas

t-siddique@northwestern.edu (TS); t-lukas@northwestern.edu (TJL)

Affiliation Department of Pharmacology, Northwestern University, Feinberg School of Medicine, Chicago, IL, 60611, United States of America

Teepu Siddique

t-siddique@northwestern.edu (TS); t-lukas@northwestern.edu (TJL)

Affiliation Department of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, IL, 60611, United States of America

Competing Interests

The authors have the following interests. Questcor Pharmaceuticals provided funds to support this project and was the sole source of Acthar gel to be used only in our animal experiments. Questcor is the owner of the drug and has retained rights for its distribution. Questcor is conducting clinical trials for ALS and other diseases. There are no restrictions on data generated during the course of the study. There are no further patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: TJL TS. Performed the experiments: TJL HA. Analyzed the data: TJL TS. Wrote the paper: HA TJL TS.