About the Authors

Yi He

Affiliation NordicBioscience, Herlev, Danmark

Qinlong Zheng

Affiliation NordicBioscience, Herlev, Danmark

MengMeng Jiang

Affiliation NordicBioscience China, Beijing, P.R. China

Shu Sun

Affiliation NordicBioscience, Herlev, Danmark

Thorbjørn G. Christiansen

Affiliation Orthopedic Department, Gentofte University Hospital, Hellerup, Denmark

Moustapha Kassem

Affiliation Molecular Endocrinology Laboratory (KMEB), Odense University Hospital, Odense, Denmark

Morten A. Karsdal

Affiliation NordicBioscience, Herlev, Danmark

Anne C. Bay-Jensen

acbj@nordicbioscience.com

Affiliation NordicBioscience, Herlev, Danmark

Competing Interests

The authors have the following interests. Yi He, Qinlong Zheng, MengMeng Jiang, ShuSun, Morten A. Karsdal and Anne C. Bay-Jensen are employed by Nordic Bioscience. MAK and ACBJ hold shares in Nordic Bioscience. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: YH ACBJ MAK. Performed the experiments: YH QZ MMJ. Analyzed the data: YH ACBJ. Contributed reagents/materials/analysis tools: SS. Wrote the paper: YH ACBJ. Reviewed the manuscripts and provided expert advice: MK TGC.