About the Authors
- Manuel Romero-Gómez
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* E-mail: mromerogomez@us.es
Affiliation UCM Digestive Diseases & ciberehd, Valme University Hospital, Sevilla, Spain
- Juan Turnes
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Affiliation Complejo Hospitalario de Pontevedra, Pontevedra, Spain
- Javier Ampuero
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Affiliation UCM Digestive Diseases & ciberehd, Valme University Hospital, Sevilla, Spain
- Itziar Oyagüez
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Affiliation Pharmacoeconomics & Outcomes Research Iberia, Madrid, Spain
- Beatriz Cuenca
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Affiliation Hospital Infanta Cristina, Parla, Madrid, Spain
- Juan Gonzalez-Garcia
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Affiliation Hospital Universitario La Paz, Madrid, Spain
- Belén Muñoz-Molina
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Affiliation Unidad de Hepatología, Roche Farma, Spain
- Rocio Aguilar
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Affiliation FISEVI, Sevilla, Spain
- Sandra Leal
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Affiliation FISEVI, Sevilla, Spain
- Ramon Planas
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Affiliation Hospital Germans Trias i Pujol & ciberehd, Badalona, Barcelona, Spain
- Javier Garcia-Samaniego
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Affiliation Hospital Carlos III & ciberehd, Madrid, Spain
- Moises Diago
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Affiliation Hospital General de Valencia, Valencia, Spain
- Javier Crespo
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Affiliation Hospital Marqués de Valdecilla, Santander, Spain
- Jose Luis Calleja
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Affiliation Hospital Puerta de Hierro, Madrid, Spain
- Miguel Angel Casado
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Affiliation Pharmacoeconomics & Outcomes Research Iberia, Madrid, Spain
- Ricard Sola
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Affiliation Hospital del Mar, IMIM, Barcelona, Spain
Competing Interests
Co-authors Itziar Oyagüez and Miguel Ángel Casado are employed by Pharmacoeconomics & Outcomes Research Iberia. The study was funded by an unrestricted grant from Roche Farma (Spain). The Optim tool has been patented (P201330731). There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Wrote the paper: JA MR-G. Guarantor of the data: MR-G. Cost-analysis: IO MAC. Acquisition of data: MR-G JT JA BC JG-G BM-M RA SL RP JG-S MD JC JLC RS.