About the Authors

Soline Aubry

Contributed equally to this work with: Soline Aubry, William Shin

Affiliation Taub Institute for Research on Alzheimer's Disease & the Aging Brain and the Department of Pathology & Cell Biology, Columbia University, New York, NY, 10032, United States of America

William Shin

Contributed equally to this work with: Soline Aubry, William Shin

Affiliations Department of Systems Biology, Columbia University, New York, NY, 10032, United States of America, Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, 10032, United States of America, Department of Biological Sciences, Columbia University, New York, NY, 10027, United States of America

John F. Crary

Affiliation Taub Institute for Research on Alzheimer's Disease & the Aging Brain and the Department of Pathology & Cell Biology, Columbia University, New York, NY, 10032, United States of America

Roger Lefort

Affiliation Taub Institute for Research on Alzheimer's Disease & the Aging Brain and the Department of Pathology & Cell Biology, Columbia University, New York, NY, 10032, United States of America

Yasir H. Qureshi

Affiliation Taub Institute for Research on Alzheimer's Disease & the Aging Brain and the Department of Pathology & Cell Biology, Columbia University, New York, NY, 10032, United States of America

Celine Lefebvre

Affiliations Department of Systems Biology, Columbia University, New York, NY, 10032, United States of America, Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, 10032, United States of America, Inserm Unit U981, Institut Gustave Roussy, 94805, Villejuif, France

Andrea Califano

ac2248@columbia.edu (AC); mls7@columbia.edu (MLS)

Affiliations Department of Systems Biology, Columbia University, New York, NY, 10032, United States of America, Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, 10032, United States of America, Department of Biological Sciences, Columbia University, New York, NY, 10027, United States of America

Michael L. Shelanski

ac2248@columbia.edu (AC); mls7@columbia.edu (MLS)

Affiliation Taub Institute for Research on Alzheimer's Disease & the Aging Brain and the Department of Pathology & Cell Biology, Columbia University, New York, NY, 10032, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SA WS JFC AC MLS. Performed the experiments: SA WS RL YHQ. Analyzed the data: SA WS JFC CL AC MLS. Contributed reagents/materials/analysis tools: SA WS AC MLS. Wrote the paper: SA WS JFC AC MLS.