About the Authors

Rui Jia

Contributed equally to this work with: Rui Jia, Shilei Ding

Current address: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH) Building 35, Rm 2F240A, 35A Convent Drive, Bethesda, Maryland, 20892, United States of America

Affiliations Key Laboratory of Molecular Microbiology and Biotechnology (Ministry of Education) and Key Laboratory of Microbial Functional Genomics (Tianjin), College of Life Sciences, Nankai University, Tianjin, 300071, China, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec, H3T 1E2, Canada

Shilei Ding

Contributed equally to this work with: Rui Jia, Shilei Ding

Affiliations Lady Davis Institute, Jewish General Hospital, Montreal, Quebec, H3T 1E2, Canada, Department of Medicine, McGill University, Montreal, Quebec, H3A 2B4, Canada

Qinghua Pan

Affiliation Lady Davis Institute, Jewish General Hospital, Montreal, Quebec, H3T 1E2, Canada

Shan-Lu Liu

Affiliation Department of Molecular Microbiology & Immunology, School of Medicine, Bond Life Sciences Center, University of Missouri, Columbia, Missouri, 65211–7310, United States of America

Wentao Qiao

Affiliation Key Laboratory of Molecular Microbiology and Biotechnology (Ministry of Education) and Key Laboratory of Microbial Functional Genomics (Tianjin), College of Life Sciences, Nankai University, Tianjin, 300071, China

Chen Liang

chen.liang@mcgill.ca

Affiliations Lady Davis Institute, Jewish General Hospital, Montreal, Quebec, H3T 1E2, Canada, Department of Medicine, McGill University, Montreal, Quebec, H3A 2B4, Canada

Competing Interests

CL is a PLOS ONE Editorial Board member. This does not alter the authors’ adherence to PLOS ONE Editorial policies and criteria.

Author Contributions

Conceived and designed the experiments: CL WQ. Performed the experiments: RJ SD QP. Analyzed the data: RJ SD SLL CL. Contributed reagents/materials/analysis tools: SLL CL. Wrote the paper: SLL WQ CL.