About the Authors

April M. Weissmiller

Affiliation Department of Neurosciences, University of California San Diego, San Diego, California, United States of America

Orlangie Natera-Naranjo

Affiliation Department of Neurosciences, University of California San Diego, San Diego, California, United States of America

Sol M. Reyna

Affiliation Department of Cellular and Molecular Medicine, University of California San Diego, San Diego, California, United States of America

Matthew L. Pearn

Affiliations Department of Anesthesiology, University of California San Diego, San Diego, California, United States of America, V.A. San Diego Healthcare System, San Diego, California, United States of America

Xiaobei Zhao

Affiliation Department of Neurosciences, University of California San Diego, San Diego, California, United States of America

Phuong Nguyen

Affiliation Department of Neurosciences, University of California San Diego, San Diego, California, United States of America

Soan Cheng

Affiliation Department of Neurosciences, University of California San Diego, San Diego, California, United States of America

Lawrence S. B. Goldstein

Affiliation Department of Cellular and Molecular Medicine, University of California San Diego, San Diego, California, United States of America

Rudolph E. Tanzi

Affiliation Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Steven L. Wagner

Affiliation Department of Neurosciences, University of California San Diego, San Diego, California, United States of America

William C. Mobley

wmobley@ucsd.edu (WCM); chw049@ucsd.edu (CW)

Affiliation Department of Neurosciences, University of California San Diego, San Diego, California, United States of America

Chengbiao Wu

wmobley@ucsd.edu (WCM); chw049@ucsd.edu (CW)

Affiliation Department of Neurosciences, University of California San Diego, San Diego, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AMW SLW WCM CW. Performed the experiments: AMW ONN SMR MLP XZ PN CW. Analyzed the data: AMW ONN MLP PN SLW WCM CW. Contributed reagents/materials/analysis tools: SC LSBG SLW RET. Wrote the paper: AMW WCM CW.