Progressive Decrease in the Potential Usefulness of Meningococcal Serogroup B Vaccine (4CMenB, Bexsero®) in Gipuzkoa, Northern Spain

Emilio Pérez-Trallero; Olatz Esnal; José M. Marimón

doi:10.1371/journal.pone.0116024

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Open Access

Peer-reviewed

Research Article

Progressive Decrease in the Potential Usefulness of Meningococcal Serogroup B Vaccine (4CMenB, Bexsero®) in Gipuzkoa, Northern Spain

Emilio Pérez-Trallero ,

* E-mail: mikrobiol@terra.com

Affiliations Microbiology Service and Reference Laboratory for Meningococcal Infections of the Basque Country, Hospital Donostia-IIS Biodonostia, San Sebastián, Spain, Biomedical Research Centre Network for Respiratory Diseases (CIBERES), San Sebastián, Spain, Faculty of Medicine, University of the Basque Country UPV/EHU, San Sebastián, Spain
⨯
Olatz Esnal,

Affiliation Biomedical Research Centre Network for Respiratory Diseases (CIBERES), San Sebastián, Spain
⨯
José M. Marimón

Affiliations Microbiology Service and Reference Laboratory for Meningococcal Infections of the Basque Country, Hospital Donostia-IIS Biodonostia, San Sebastián, Spain, Biomedical Research Centre Network for Respiratory Diseases (CIBERES), San Sebastián, Spain
⨯

Progressive Decrease in the Potential Usefulness of Meningococcal Serogroup B Vaccine (4CMenB, Bexsero®) in Gipuzkoa, Northern Spain

Emilio Pérez-Trallero,
Olatz Esnal,
José M. Marimón

Published: December 26, 2014
https://doi.org/10.1371/journal.pone.0116024

About the Authors

Emilio Pérez-Trallero

* E-mail: mikrobiol@terra.com

Affiliations Microbiology Service and Reference Laboratory for Meningococcal Infections of the Basque Country, Hospital Donostia-IIS Biodonostia, San Sebastián, Spain, Biomedical Research Centre Network for Respiratory Diseases (CIBERES), San Sebastián, Spain, Faculty of Medicine, University of the Basque Country UPV/EHU, San Sebastián, Spain

Olatz Esnal

Affiliation Biomedical Research Centre Network for Respiratory Diseases (CIBERES), San Sebastián, Spain

José M. Marimón

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EPT OE. Performed the experiments: OE JMM. Analyzed the data: EPT OE JMM. Contributed reagents/materials/analysis tools: EPT OE JMM. Wrote the paper: EPT OE.

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Vaccines
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Neisseria meningitidis
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Meningococcal disease
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Cloning
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Antigen encapsulation
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Antigenic variation
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Europe
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Spain
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