About the Authors

Mark R. Kelley

mkelley@iu.edu

Affiliations Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indianapolis, Indiana, United States of America, Department of Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

Yanlin Jiang

Affiliation Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indianapolis, Indiana, United States of America

Chunlu Guo

Affiliation Department of Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

April Reed

Affiliation Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indianapolis, Indiana, United States of America

Hongdi Meng

Affiliation Department of Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

Michael R. Vasko

Affiliation Department of Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

Competing Interests

MRK declares that he is employed as a consultant at ApeX Therapeutics, which has licensed IP from his work. No other authors have any potential conflicts of interest to declare. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MRK MRV. Performed the experiments: YJ CG AR HM. Analyzed the data: MRK MRV. Contributed reagents/materials/analysis tools: MRK MRV. Wrote the paper: MRK MRV.