About the Authors

Syed Irfan Raza

Affiliations Department of Biochemistry, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan, Army Medical College, National University of Science and Technology NUST, Islamabad, Pakistan

Dost Muhammad

Affiliation Department of Biochemistry, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan

Abid Jan

Affiliation Department of Biochemistry, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan

Raja Hussain Ali

Affiliation Department of Biochemistry, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan

Mubashir Hassan

Affiliation National Center for Bioinformatics, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan

Wasim Ahmad

Affiliation Department of Biochemistry, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan

Sajid Rashid

sajidrwp@yahoo.co.uk

Affiliation National Center for Bioinformatics, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Performed the experiments: SIR DM AJ RHA. Analyzed the data: WA SR. Contributed reagents/materials/analysis tools: WA. Contributed to the writing of the manuscript: SIR WA SR. Blood collection from families: DM AJ RHA. Conceived and performed in silico analysis: SR MH.