Important Role of Autophagy in Endothelial Cell Response to Ionizing Radiation

Dimitra Kalamida; Ilias V. Karagounis; Alexandra Giatromanolaki; Michael I. Koukourakis

doi:10.1371/journal.pone.0102408

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Open Access

Peer-reviewed

Research Article

Important Role of Autophagy in Endothelial Cell Response to Ionizing Radiation

Dimitra Kalamida,

Affiliation Department of Radiotherapy/Oncology, Democritus University of Thrace, and University General Hospital of Alexandroupolis, Alexandroupolis, Greece
⨯
Ilias V. Karagounis,

Affiliation Department of Radiotherapy/Oncology, Democritus University of Thrace, and University General Hospital of Alexandroupolis, Alexandroupolis, Greece
⨯
Alexandra Giatromanolaki,

Affiliation Department of Pathology, Democritus University of Thrace, and University General Hospital of Alexandroupolis, Alexandroupolis, Greece
⨯
Michael I. Koukourakis

* E-mail: targ@her.forthnet.gr

Affiliation Department of Radiotherapy/Oncology, Democritus University of Thrace, and University General Hospital of Alexandroupolis, Alexandroupolis, Greece
⨯

Important Role of Autophagy in Endothelial Cell Response to Ionizing Radiation

Dimitra Kalamida,
Ilias V. Karagounis,
Alexandra Giatromanolaki,
Michael I. Koukourakis

Published: July 10, 2014
https://doi.org/10.1371/journal.pone.0102408

About the Authors

Dimitra Kalamida

Affiliation Department of Radiotherapy/Oncology, Democritus University of Thrace, and University General Hospital of Alexandroupolis, Alexandroupolis, Greece

Ilias V. Karagounis

Affiliation Department of Radiotherapy/Oncology, Democritus University of Thrace, and University General Hospital of Alexandroupolis, Alexandroupolis, Greece

Alexandra Giatromanolaki

Affiliation Department of Pathology, Democritus University of Thrace, and University General Hospital of Alexandroupolis, Alexandroupolis, Greece

Michael I. Koukourakis

* E-mail: targ@her.forthnet.gr

Affiliation Department of Radiotherapy/Oncology, Democritus University of Thrace, and University General Hospital of Alexandroupolis, Alexandroupolis, Greece

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DK IK AG MIK. Performed the experiments: DK IK AG MIK. Analyzed the data: DK IK AG MIK. Contributed reagents/materials/analysis tools: DK IK AG MIK. Wrote the paper: DK IK AG MIK.

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Autophagic cell death
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Endothelial cells
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Cytoplasm
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Radiation therapy
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Confocal microscopy
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Lysosomes
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Small interfering RNA
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Transcription factors
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