About the Authors

Susanna Esposito

susanna.esposito@unimi.it

Affiliation Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy

Alberto Zampiero

Affiliation Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy

Lorenza Pugni

Affiliation Neonatal Intensive Care Unit, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy

Silvia Tabano

Affiliation Genetic Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy

Claudio Pelucchi

Affiliation Department of Epidemiology Unit, IRCCS Mario Negri Institute for Pharmacological Research, Milan, Italy

Beatrice Ghirardi

Affiliation Neonatal Intensive Care Unit, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy

Leonardo Terranova

Affiliation Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy

Monica Miozzo

Affiliation Genetic Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy

Fabio Mosca

Affiliation Neonatal Intensive Care Unit, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy

Nicola Principi

Affiliation Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy

Competing Interests

Co-author and corresponding author Susanna Esposito is a PLOS ONE Editorial Board Member but this does not alter the authors' adherence to PLOS ONE Editorial policies and criteria.

Author Contributions

Conceived and designed the experiments: SE NP. Performed the experiments: AZ ST LT MM. Analyzed the data: CP. Contributed reagents/materials/analysis tools: SE AZ LP ST BG LT MM FM NP. Contributed to the writing of the manuscript: SE NP. Clinical evaluation: LP BG FM.