The “Grep” Command But Not FusionMap, FusionFinder or ChimeraScan Captures the CIC-DUX4 Fusion Gene from Whole Transcriptome Sequencing Data on a Small Round Cell Tumor with t(4;19)(q35;q13)

Ioannis Panagopoulos; Ludmila Gorunova; Bodil Bjerkehagen; Sverre Heim

doi:10.1371/journal.pone.0099439

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Open Access

Peer-reviewed

Research Article

The “Grep” Command But Not FusionMap, FusionFinder or ChimeraScan Captures the CIC-DUX4 Fusion Gene from Whole Transcriptome Sequencing Data on a Small Round Cell Tumor with t(4;19)(q35;q13)

Ioannis Panagopoulos ,

* E-mail: ioannis.panagopoulos@rr-research.no

Affiliations Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway, Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Oslo, Norway
⨯
Ludmila Gorunova,

Affiliations Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway, Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Oslo, Norway
⨯
Bodil Bjerkehagen,

Affiliation Department of Pathology, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway
⨯
Sverre Heim

Affiliations Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway, Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Oslo, Norway, Faculty of Medicine, University of Oslo, Oslo, Norway
⨯

The “Grep” Command But Not FusionMap, FusionFinder or ChimeraScan Captures the CIC-DUX4 Fusion Gene from Whole Transcriptome Sequencing Data on a Small Round Cell Tumor with t(4;19)(q35;q13)

Ioannis Panagopoulos,
Ludmila Gorunova,
Bodil Bjerkehagen,
Sverre Heim

Published: June 20, 2014
https://doi.org/10.1371/journal.pone.0099439

About the Authors

Ioannis Panagopoulos

* E-mail: ioannis.panagopoulos@rr-research.no

Affiliations Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway, Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Oslo, Norway

Ludmila Gorunova

Bodil Bjerkehagen

Affiliation Department of Pathology, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway

Sverre Heim

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: IP. Performed the experiments: IP LG BB. Analyzed the data: IP. Contributed reagents/materials/analysis tools: BB SH. Wrote the paper: IP SH.

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Cancers and neoplasms
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Polymerase chain reaction
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Cell fusion
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RNA sequencing
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Ewing sarcoma
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Signal amplification
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Fusion genes
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Karyotypes
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