About the Authors
- Yuka Keyamura
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Affiliations Free Radical Research Project, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan, Division of Biological Chemistry, Department of Molecular Biology, Showa University School of Pharmacy, Tokyo, Japan
- Chifumi Nagano
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Affiliation Free Radical Research Project, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan
- Masayuki Kohashi
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Affiliation Free Radical Research Project, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan
- Manabu Niimi
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Affiliation Free Radical Research Project, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan
- Masanori Nozako
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Affiliation Free Radical Research Project, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan
- Takashi Koyama
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Affiliation Free Radical Research Project, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan
- Reiko Yasufuku
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Affiliation Free Radical Research Project, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan
- Ayako Imaizumi
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Affiliation Free Radical Research Project, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan
- Hiroyuki Itabe
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Affiliation Division of Biological Chemistry, Department of Molecular Biology, Showa University School of Pharmacy, Tokyo, Japan
- Tomohiro Yoshikawa
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* E-mail: yoshikawa.tomohiro.a@otsuka.jp
Affiliation Free Radical Research Project, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan
Competing Interests
The authors, YK, CN, MK, MN, MN, TK, RY, AI, TY are employed by Otsuka Pharmaceutical Co., Ltd, and probucol was provided by Otsuka Pharmaceutical Co., Ltd. We do not have any other declarations such as consultancy or patents. This does not alter our adherence to PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: YK TY. Performed the experiments: YK CN MK M. Niimi M. Nozako TK RY AI TY. Analyzed the data: YK CN MK HI TY. Contributed reagents/materials/analysis tools: HI. Wrote the paper: YK HI TY.