About the Authors

Junyun He

Affiliation The Biodesign Institute and School of Life Sciences, Arizona State University, Tempe, Arizona, United States of America

Huafang Lai

Affiliation The Biodesign Institute and School of Life Sciences, Arizona State University, Tempe, Arizona, United States of America

Michael Engle

Affiliation Department of Medicine, Washington University School of Medicine, St Louis, Missouri, United States of America

Sergey Gorlatov

Affiliation MacroGenics, Inc, Rockville, Maryland, United States of America

Clemens Gruber

Affiliation Department of Chemistry, University of Natural Resources and Applied Life Sciences, Vienna, Austria

Herta Steinkellner

Affiliation Department of Applied Genetics and Cell Biology, University of Natural Resources and Applied Life Sciences, Vienna, Austria

Michael S. Diamond

Affiliations Department of Medicine, Washington University School of Medicine, St Louis, Missouri, United States of America, Department of Molecular Microbiology, Washington University School of Medicine, St Louis, Missouri, United States of America, Department of Pathology & Immunology, Washington University School of Medicine, St Louis, Missouri, United States of America

Qiang Chen

qiang.chen.4@asu.edu

Affiliations The Biodesign Institute and School of Life Sciences, Arizona State University, Tempe, Arizona, United States of America, College of Technology and Innovation, Arizona State University, Mesa, Arizona, United States of America

Competing Interests

S. Gorlatov is an employee of MacroGenics, Inc, which has licensed the WNV E16 antibody from Washington University for possible commercial development. Additionally, M. Diamond is a paid consultant for MacroGenics and owns equity in MacroGenics. These relationships do not alter the authors' adherence to PLOS ONE policies on sharing data and materials. None of the other authors have a potential financial stake or conflict of interest associated with the publication of this work.

Author Contributions

Conceived and designed the experiments: QC MD HS JH HL. Performed the experiments: JH HL ME SG CG. Analyzed the data: QC MD HS JH HL ME SG CG. Contributed reagents/materials/analysis tools: QC MD HS JH HL ME SG CG. Wrote the paper: QC MD HS JH HL ME SG CG.