About the Authors

Mariena J. A. van der Plas

mjavanderplas@gmail.com

Current address: Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Lund, Sweden

Affiliations Department of Infectious Disease, Leiden University Medical Center, Leiden, The Netherlands, Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands

Anders S. Andersen

Affiliations Department of Microbiology and Infection Control, Statens Serum Institute, Copenhagen, Denmark, Novozymes A/S, Bagsvaerd, Denmark, Copenhagen Wound Healing Center, Bispebjerg Hospital, Copenhagen, Denmark

Sheresma Nazir

Affiliation Department of Infectious Disease, Leiden University Medical Center, Leiden, The Netherlands

Nico H. van Tilburg

Affiliation Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands

Peter R. Oestergaard

Affiliation Novozymes A/S, Bagsvaerd, Denmark

Karen A. Krogfelt

Affiliation Department of Microbiology and Infection Control, Statens Serum Institute, Copenhagen, Denmark

Jaap T. van Dissel

Affiliation Department of Infectious Disease, Leiden University Medical Center, Leiden, The Netherlands

Paul J. Hensbergen

Affiliation Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands

Rogier M. Bertina

Contributed equally to this work with: Rogier M. Bertina, Peter H. Nibbering

Affiliation Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands

Peter H. Nibbering

Contributed equally to this work with: Rogier M. Bertina, Peter H. Nibbering

Affiliation Department of Infectious Disease, Leiden University Medical Center, Leiden, The Netherlands

Competing Interests

Anders S. Andersen and Peter R. Oestergaard are employed by Novozymes A/S. Sterile second- and third-instar larvae of Lucilia sericata were a gift from BioMonde GmbH. There are no further patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: MJAvdP RMB PHN. Performed the experiments: MJAvdP ASA SN NHvT PRO PJH. Analyzed the data: MJAvdP ASA KAK PJH RMB. Contributed reagents/materials/analysis tools: KAK JTvD RMB PHN. Wrote the paper: MJAvdP ASA RMB PHN.