About the Authors

Margot A. Cousin

Affiliations Mayo Addiction Research Center, Mayo Clinic, Rochester, Minnesota, United States of America, Center for Clinical and Translational Science, Mayo Clinic, Rochester, Minnesota, United States of America

Jon O. Ebbert

Affiliations Mayo Addiction Research Center, Mayo Clinic, Rochester, Minnesota, United States of America, Nicotine Dependence Center, Mayo Clinic, Rochester, Minnesota, United States of America

Amanda R. Wiinamaki

Affiliation Mayo Addiction Research Center, Mayo Clinic, Rochester, Minnesota, United States of America

Mark D. Urban

Affiliation Mayo Addiction Research Center, Mayo Clinic, Rochester, Minnesota, United States of America

David P. Argue

Affiliation Mayo Addiction Research Center, Mayo Clinic, Rochester, Minnesota, United States of America

Stephen C. Ekker

Affiliations Mayo Addiction Research Center, Mayo Clinic, Rochester, Minnesota, United States of America, Center for Clinical and Translational Science, Mayo Clinic, Rochester, Minnesota, United States of America

Eric W. Klee

klee.eric@mayo.edu

Affiliations Mayo Addiction Research Center, Mayo Clinic, Rochester, Minnesota, United States of America, Center for Clinical and Translational Science, Mayo Clinic, Rochester, Minnesota, United States of America

Competing Interests

The authors have read the journal's policy and have the following conflicts: Dr. Ebbert reports grants from Pfizer and Orexigen and personal fees from GlaxoSmithKline outside the submitted work. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials. The remaining authors have declared that no competing interests exist. All authors have approved the manuscript for consideration to PLOS ONE.

Author Contributions

Conceived and designed the experiments: MAC JOE ARW MDU DPA SCE EWK. Performed the experiments: MAC ARW MDU. Analyzed the data: MAC EWK. Contributed reagents/materials/analysis tools: DPA. Wrote the paper: MAC JOE ARW MDU DPA SCE EWK.