About the Authors

Anne Hansen Ree

a.h.ree@medisin.uio.no

Affiliations Department of Oncology, Akershus University Hospital, Lørenskog, Norway, Institute of Clinical Medicine, University of Oslo, Oslo, Norway

Marie Grøn Saelen

Affiliations Department of Tumor Biology, Oslo University Hospital – Norwegian Radium Hospital, Oslo, Norway, Institute of Clinical Medicine, University of Oslo, Oslo, Norway

Erta Kalanxhi

Affiliation Department of Oncology, Akershus University Hospital, Lørenskog, Norway

Ingrid H. G. Østensen

Affiliation Department of Genes and Environment, Norwegian Institute of Public Health, Oslo, Norway

Kristina Schee

Affiliation Department of Tumor Biology, Oslo University Hospital – Norwegian Radium Hospital, Oslo, Norway

Kathrine Røe

Affiliation Department of Oncology, Akershus University Hospital, Lørenskog, Norway

Torveig Weum Abrahamsen

Affiliation Department of Tumor Biology, Oslo University Hospital – Norwegian Radium Hospital, Oslo, Norway

Svein Dueland

Affiliation Department of Oncology, Oslo University Hospital – Norwegian Radium Hospital, Oslo, Norway

Kjersti Flatmark

Affiliations Department of Tumor Biology, Oslo University Hospital – Norwegian Radium Hospital, Oslo, Norway, Department of Gastroenterological Surgery, Oslo University Hospital – Norwegian Radium Hospital, Oslo, Norway

Competing Interests

This work was supported by MSD (Norge) AS, the Norway branch of Merck & Co., Inc., directed at overheads associated with the study. Moreover, this does not alter our adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AHR SD KF. Performed the experiments: AHR MGS EK IHGØ KS KR TWA KF. Analyzed the data: AHR MGS EK KR KF. Contributed reagents/materials/analysis tools: AHR MGS EK IHGØ KS KR TWA KF. Wrote the paper: AHR. Managed patients, databases, and tissue banking: AHR MGS SD KF.