About the Authors

Kotaro Azuma

Affiliation Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Tohru Tsukui

Affiliation Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, Hidaka, Saitama, Japan

Kazuhiro Ikeda

Affiliation Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, Hidaka, Saitama, Japan

Sachiko Shiba

Affiliation Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, Hidaka, Saitama, Japan

Kimie Nakagawa

Affiliation Department of Hygienic Sciences, Kobe Pharmaceutical University, Kobe, Hyogo, Japan

Toshio Okano

Affiliation Department of Hygienic Sciences, Kobe Pharmaceutical University, Kobe, Hyogo, Japan

Tomohiko Urano

Affiliation Department of Anti-Aging Medicine, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Kuniko Horie-Inoue

Affiliation Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, Hidaka, Saitama, Japan

Yasuyoshi Ouchi

Affiliation Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Masahito Ikawa

Affiliation Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan

Satoshi Inoue

INOUE-GER@h.u-tokyo.ac.jp

Affiliations Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan, Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, Hidaka, Saitama, Japan, Department of Anti-Aging Medicine, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KA TT SI. Performed the experiments: KA TT KI SS KN MI. Analyzed the data: KA TT KI SS KN TO MI SI. Contributed reagents/materials/analysis tools: TO TU KHI YO MI SI. Wrote the paper: KA TT KI KHI SI.