About the Authors

Trent Fowler

Affiliation Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, Massachusetts, United States of America

Payel Ghatak

Affiliation Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, Massachusetts, United States of America

David H. Price

Affiliation Biochemistry Department, University of Iowa, Iowa City, Iowa, United States of America

Ronald Conaway

Affiliation Stowers Institute for Medical Research, Kansas City, Missouri, United States of America

Joan Conaway

Affiliation Stowers Institute for Medical Research, Kansas City, Missouri, United States of America

Cheng-Ming Chiang

Affiliation Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

James E. Bradner

Affiliation Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America

Ali Shilatifard

Affiliation Stowers Institute for Medical Research, Kansas City, Missouri, United States of America

Ananda L. Roy

ananda.roy@tufts.edu

Affiliations Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, Massachusetts, United States of America, Program in Genetics, Sackler School of Biomedical Science, Tufts University School of Medicine, Boston, Massachusetts, United States of America, Program in Immunology, Sackler School of Biomedical Science, Tufts University School of Medicine, Boston, Massachusetts, United States of America

Competing Interests

J.E.B. has a minority equity allocation in Tensha Therapeutics. This does not alter the authors′ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: TF ALR. Performed the experiments: TF PG. Analyzed the data: DHP RC JC C-MC JEB AS. Contributed reagents/materials/analysis tools: DHP RC JC C-MC JEB AS. Wrote the paper: TF ALR. Helped with review and revision of the manuscript: DHP RC JC C-MC JEB AS.