Resveratrol Inhibits Cisplatin-Induced Epithelial-to-Mesenchymal Transition in Ovarian Cancer Cell Lines

Sébastien Baribeau; Parvesh Chaudhry; Sophie Parent; Éric Asselin

doi:10.1371/journal.pone.0086987

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Open Access

Peer-reviewed

Research Article

Resveratrol Inhibits Cisplatin-Induced Epithelial-to-Mesenchymal Transition in Ovarian Cancer Cell Lines

Sébastien Baribeau,

Affiliation Research Group in Molecular Oncology and Endocrinology, Department of Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, Canada
⨯
Parvesh Chaudhry,

Affiliation Research Group in Molecular Oncology and Endocrinology, Department of Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, Canada
⨯
Sophie Parent,

Affiliation Research Group in Molecular Oncology and Endocrinology, Department of Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, Canada
⨯
Éric Asselin

* E-mail: eric.asselin@uqtr.ca

Affiliation Research Group in Molecular Oncology and Endocrinology, Department of Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, Canada
⨯

Resveratrol Inhibits Cisplatin-Induced Epithelial-to-Mesenchymal Transition in Ovarian Cancer Cell Lines

Sébastien Baribeau,
Parvesh Chaudhry,
Sophie Parent,
Éric Asselin

Published: January 22, 2014
https://doi.org/10.1371/journal.pone.0086987

About the Authors

Sébastien Baribeau

Affiliation Research Group in Molecular Oncology and Endocrinology, Department of Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, Canada

Parvesh Chaudhry

Affiliation Research Group in Molecular Oncology and Endocrinology, Department of Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, Canada

Sophie Parent

Affiliation Research Group in Molecular Oncology and Endocrinology, Department of Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, Canada

Éric Asselin

* E-mail: eric.asselin@uqtr.ca

Affiliation Research Group in Molecular Oncology and Endocrinology, Department of Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SB PC EA. Performed the experiments: SB PC SP. Analyzed the data: SB PC EA. Contributed reagents/materials/analysis tools: SB PC EA. Wrote the paper: SB EA.

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Cancer treatment
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Ovarian cancer
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Apoptosis
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Autophagic cell death
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Vimentin
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Cell death
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ERK signaling cascade
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