About the Authors

Jason H. Stafford

* Email: jason006@stanford.edu

Affiliation Department of Pharmacology, The Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Guiyang Hao

Affiliation Department of Radiology, The Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Anne M. Best

Affiliation Department of Pharmacology, The Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Xiankai Sun

Affiliation Department of Radiology, The Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Philip E. Thorpe

† Deceased.

Affiliation Department of Pharmacology, The Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Competing Interests

The authors have the following interests: This study was partly funded by a sponsored research agreement with Peregrine Pharmaceuticals Inc. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed in the online guide for authors.

Author Contributions

Conceived and designed the experiments: JHS GH XS PET. Performed the experiments: AMB. Analyzed the data: JHS GH XS PET. Contributed reagents/materials/analysis tools: JHS GH XS PET. Wrote the manuscript: JHS PET.