About the Authors

Nathalie Compté

Affiliation Institute for Medical Immunology (IMI), Université Libre de Bruxelles, Charleroi, Belgium

Karim Zouaoui Boudjeltia

Affiliation Experimental Medicine Laboratory (Unit 222), Université Libre de Bruxelles, Hôpital A. Vésale, Montigny-Le-Tilleul, Belgium

Michel Vanhaeverbeek

Affiliation Experimental Medicine Laboratory (Unit 222), Université Libre de Bruxelles, Hôpital A. Vésale, Montigny-Le-Tilleul, Belgium

Sandra De Breucker

Affiliation Service de Gériatrie, Hôpital Erasme, Bruxelles, Belgium

Thierry Pepersack

Affiliation Service de Gériatrie, Hôpital Erasme, Bruxelles, Belgium

Joel Tassignon

Affiliation ImmuneHealth, Charleroi, Belgium

Anne Trelcat

Affiliation ImmuneHealth, Charleroi, Belgium

Stanislas Goriely

stgoriel@ulb.ac.be

Affiliation Institute for Medical Immunology (IMI), Université Libre de Bruxelles, Charleroi, Belgium

Competing Interests

The study was partly supported GlaxoSmithKline Biologicals. Authors JT and AT are employed by ImmuneHealth, Charleroi, Belgium. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: NC TP KZB MV SG. Performed the experiments: NC AT. Analyzed the data: NC KZB MV SG. Contributed reagents/materials/analysis tools: NC SDB JT. Wrote the manuscript: NC TP MV SG.