About the Authors

Hung-Yu Yang

Contributed equally to this work with: Hung-Yu Yang, Ya-Fen Hsu

Affiliation Division of Cardiology, Taipei Medical University-Wan Fang Hospital, Taipei, Taiwan

Ya-Fen Hsu

Contributed equally to this work with: Hung-Yu Yang, Ya-Fen Hsu

Affiliation Division of General Surgery, Department of Surgery, Landseed Hospital, Taoyuan, Taiwan

Pei-Ting Chiu

Affiliation Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan

Shiau-Jing Ho

Affiliation NatureWise Biotech & Medicals Corporation, Taipei, Taiwan

Chi-Han Wang

Affiliation NatureWise Biotech & Medicals Corporation, Taipei, Taiwan

Chih-Chin Chi

Affiliation NatureWise Biotech & Medicals Corporation, Taipei, Taiwan

Yu-Han Huang

Affiliation Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan

Cheng-Feng Lee

Affiliation NatureWise Biotech & Medicals Corporation, Taipei, Taiwan

Ying-Shiuan Li

Affiliation NatureWise Biotech & Medicals Corporation, Taipei, Taiwan

George Ou

Affiliation Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

Ming-Jen Hsu

aspirin@tmu.edu.tw

Affiliations Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan, Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

Competing Interests

NatureWise Biotech & Medicals Corporation is the developer and patent holder on BMX and its derivatives in several countries. Patent name: CINAMIC COMPOUNDS AND DERIVATIVES THEREFROM FOR THE INHIBITION OF HISTONE DEACETYLASE. Patent number: US7994357. Shiau-Jing Ho, Chi-Han Wang, Chih-Chin Chi, Cheng-Feng Lee and Ying-Shiuan Li are employed by NatureWise Biotech & Medicals Corporation. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: HYY YFH MJH. Performed the experiments: PTC YHH MJH. Analyzed the data: HYY YFH PTC YHH MJH. Contributed reagents/materials/analysis tools: SJH CHW CCC CFL YSL. Wrote the paper: HYY YFH GO MJH.