About the Authors
- Jia Gao
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Affiliations State Key Laboratory for Conservation and Utilization of Subtropical Agro-biosciences, The Key Laboratory of Ministry of Education for Microbial and Plant Genetic Engineering, and College of Life Science and Technology, Guangxi University, Nanning, Guangxi, China, Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America
- Byung Hak Ha
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Affiliation Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America
- Hua Jane Lou
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Affiliation Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America
- Elizabeth M. Morse
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Affiliations Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America, Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut, United States of America
- Rong Zhang
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Affiliation Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America
- David A. Calderwood
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Affiliations Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America, Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut, United States of America, Yale Cancer Center, Yale University School of Medicine, New Haven, Connecticut, United States of America
- Benjamin E. Turk
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Affiliations Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America, Yale Cancer Center, Yale University School of Medicine, New Haven, Connecticut, United States of America
- Titus J. Boggon
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* E-mail: titus.boggon@yale.edu
Affiliations Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America, Yale Cancer Center, Yale University School of Medicine, New Haven, Connecticut, United States of America
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: JG BET TJB. Performed the experiments: JG BHH HJL EMM RZ. Analyzed the data: JG BHH HJL EMM DAC BET TJB. Contributed reagents/materials/analysis tools: JG BHH HJL EMM RZ DAC BET TJB. Wrote the paper: JG BHH EMM DAC BET TJB. Molecular biology, protein purification and crystallography: JG. Kinase assay: BHH. Kinase substrate specificity assay: HJL. Cell based assay: EMM. Support: RZ.