About the Authors

Christine Tkaczyk

Affiliation Department of Infectious Disease, MedImmune, LLC, Gaithersburg, Maryland, United States of America

Melissa M. Hamilton

Affiliation Department of Infectious Disease, MedImmune, LLC, Gaithersburg, Maryland, United States of America

Vivekananda Datta

Affiliation Pathology Department, MedImmune, LLC, Gaithersburg, Maryland, United States of America

Xiang Ping Yang

Affiliation Department of Respiratory, Inflammatory and Autoimmune Diseases, MedImmune, LLC, Gaithersburg, Maryland, United States of America

Jamese J. Hilliard

Affiliation Department of Infectious Disease, MedImmune, LLC, Gaithersburg, Maryland, United States of America

Geoffrey L. Stephens

Affiliation Department of Respiratory, Inflammatory and Autoimmune Diseases, MedImmune, LLC, Gaithersburg, Maryland, United States of America

Agnieszka Sadowska

Affiliation Department of Infectious Disease, MedImmune, LLC, Gaithersburg, Maryland, United States of America

Lei Hua

Affiliation Department of Infectious Disease, MedImmune, LLC, Gaithersburg, Maryland, United States of America

Terrence O’Day

Affiliation Biostatistics Department, MedImmune, LLC, Gaithersburg, Maryland, United States of America

JoAnn Suzich

Affiliation Department of Infectious Disease, MedImmune, LLC, Gaithersburg, Maryland, United States of America

Charles Kendall Stover

Affiliation Department of Infectious Disease, MedImmune, LLC, Gaithersburg, Maryland, United States of America

Bret R. Sellman

sellmanb@medimmune.com

Affiliation Department of Infectious Disease, MedImmune, LLC, Gaithersburg, Maryland, United States of America

Competing Interests

All authors are employees of MedImmune, LLC, (a wholly owned subsidiary of AstraZeneca Pharmaceuticals) whose company funded this study. The monoclonal antibody described in this manuscript is included in a pending patent application. There are no further patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: CT MMH XPY GLS BRS. Performed the experiments: CT MMH VD XPY AS. Analyzed the data: CT MMH VD XPY AS TO BRS. Contributed reagents/materials/analysis tools: LH JJH. Wrote the paper: CT JS CKS BRS.