About the Authors

Feng Zhang

Contributed equally to this work with: Feng Zhang, Jinlong Liang

Affiliation Key Laboratory of Environment and Gene Related Diseases of Ministry Education, Faculty of Public Health, College of Medicine, Xi’an Jiaotong University, Xi’an, Shaanxi, China

Jinlong Liang

Contributed equally to this work with: Feng Zhang, Jinlong Liang

Affiliation BGI-Shenzhen, Shenzhen, China

Xiong Guo

guox@mail.xjtu.edu.cn (XG); wangjun30@gmail.com (JW)

Affiliation Key Laboratory of Environment and Gene Related Diseases of Ministry Education, Faculty of Public Health, College of Medicine, Xi’an Jiaotong University, Xi’an, Shaanxi, China

Yingang Zhang

Affiliation Department of Orthopedics, First Affiliated Hospital of Medical College of Xi’an Jiaotong University, Xi’an, Shaanxi, China

Yan Wen

Affiliation Key Laboratory of Environment and Gene Related Diseases of Ministry Education, Faculty of Public Health, College of Medicine, Xi’an Jiaotong University, Xi’an, Shaanxi, China

Qiang Li

Affiliation Department of Orthopedics, First People’s Hospital of Longxi County, Gansu, China

Zengtie Zhang

Affiliation Key Laboratory of Environment and Gene Related Diseases of Ministry Education, Faculty of Public Health, College of Medicine, Xi’an Jiaotong University, Xi’an, Shaanxi, China

Weijuan Ma

Affiliation Key Laboratory of Environment and Gene Related Diseases of Ministry Education, Faculty of Public Health, College of Medicine, Xi’an Jiaotong University, Xi’an, Shaanxi, China

Lanlan Dai

Affiliation BGI-Shenzhen, Shenzhen, China

Xuanzhu Liu

Affiliation BGI-Shenzhen, Shenzhen, China

Ling Yang

Affiliation BGI-Tianjin, Tianjin, China

Jun Wang

guox@mail.xjtu.edu.cn (XG); wangjun30@gmail.com (JW)

Affiliations BGI-Shenzhen, Shenzhen, China, Department of Biology, University of Copenhagen, Copenhagen, Denmark, King Abdulaziz University, Jeddah, Saudi Arabia

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: FZ XG JW. Performed the experiments: FZ JLL YW ZTZ XZL LY. Analyzed the data: FZ LLD WJM. Contributed reagents/materials/analysis tools: QL YGZ. Wrote the paper: FZ XG.