About the Authors

Bo-Ruei Chen

Current address: Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA

Affiliations Department of Molecular Genetics, Cleveland Clinic Lerner College of Medicine at Case Western Reserve University, Cleveland, Ohio, USA, Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America, Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America

Yanhui Li

Affiliations Department of Molecular Genetics, Cleveland Clinic Lerner College of Medicine at Case Western Reserve University, Cleveland, Ohio, USA, Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America

Jessica R. Eisenstatt

Current address: Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA

Affiliations Department of Molecular Genetics, Cleveland Clinic Lerner College of Medicine at Case Western Reserve University, Cleveland, Ohio, USA, Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America

Kurt W. Runge

rungek@ccf.org

Affiliations Department of Molecular Genetics, Cleveland Clinic Lerner College of Medicine at Case Western Reserve University, Cleveland, Ohio, USA, Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: B-RC YL JRE KWR. Performed the experiments: B-RC YL JRE. Analyzed the data: B-RC YL JRE KWR. Contributed reagents/materials/analysis tools: B-RC YL JRE KWR. Wrote the manuscript: B-RC KWR.