About the Authors

Yi-Ru Chen

Affiliations Structural Biology Program, National Yang-Ming University, Taipei, Taiwan, R.O.C, Department and Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan, R.O.C

Hsien-bin Huang

Affiliation Department of Life Science and Institute of Molecular Biology, National Chung Cheng University, Chia-Yi, Taiwan, R.O.C

Chi-Jen Lo

Affiliations Structural Biology Program, National Yang-Ming University, Taipei, Taiwan, R.O.C, Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C, Institute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei, Taiwan, R.O.C

Chih-Ching Wang

Affiliations Structural Biology Program, National Yang-Ming University, Taipei, Taiwan, R.O.C, Institute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei, Taiwan, R.O.C

Li-Kang Ho

Affiliation Department and Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan, R.O.C

Hsin-Tzu Liu

Affiliation Voiding Dysfunction Therapeutic Center in the Research Department, Buddhist Tzu Chi General Hospital, Hualien, Taiwan, R.O.C

Ming-Shi Shiao

Affiliation Department of Life Science, Chang Gung University, Kwei-Shan Tao-Yuan, Taiwan, R.O.C

Ta-Hsien Lin

chen15@mmc.edu.tw (YCC); thlin@vghtpe.gov.tw (THL)

Affiliations Structural Biology Program, National Yang-Ming University, Taipei, Taiwan, R.O.C, Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C, Institute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei, Taiwan, R.O.C

Yi-Cheng Chen

chen15@mmc.edu.tw (YCC); thlin@vghtpe.gov.tw (THL)

Affiliation Department of Medicine, MacKay Medical College, New Taipei City, Taiwan, R.O.C

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YRC THL YCC. Performed the experiments: YRC CJL CCW. Analyzed the data: YRC THL YCC. Contributed reagents/materials/analysis tools: HBH LKH HTL MSS THL YCC. Wrote the paper: YRC THL YCC.