About the Authors

Nils Schallner

nils.schallner@uniklinik-freiburg.de

Affiliation Department of Anesthesiology, Division for Experimental Anesthesiology, University Medical Center Freiburg, Germany

Carlos C. Romão

Affiliations Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal, Alfama Limitida, Instituto de Biologia Experimental e Tecnológica, Oeiras, Portugal

Julia Biermann

Affiliation University Eye Hospital, University Medical Center Freiburg, Germany

Wolf A. Lagrèze

Affiliation University Eye Hospital, University Medical Center Freiburg, Germany

Leo E. Otterbein

Affiliation Beth Israel Deaconess Medical Center, Department of Surgery, Harvard Medical School, Boston, Massachusetts, United States of America

Hartmut Buerkle

Affiliation Department of Anesthesiology, Division for Experimental Anesthesiology, University Medical Center Freiburg, Germany

Torsten Loop

Affiliation Department of Anesthesiology, Division for Experimental Anesthesiology, University Medical Center Freiburg, Germany

Ulrich Goebel

Affiliation Department of Anesthesiology, Division for Experimental Anesthesiology, University Medical Center Freiburg, Germany

Competing Interests

The authors have read the journal's policy and have the following conflicts: Author Carlos C. Romão is a co-founder, administrator and scientific officer of the company Alfama Lda. where he has equity interests. CC Romão is an inventor in Patent-No.: US 2011/0038955 A1 2011 where ALF186 exemplifies the protection of the stomach against NSAID generated ulcers by the administration of CORMs, and is therefore irrelevant for the matter of the present article. The drug profile of ALF186 is published in detail in: Anästhesiologische Universitätsklinik Prof. Karl-Wilhelm Koch, PhD Academic Editor Public Library of Science – PLOS ONE Dr. med. Nils Schallner Hugstetter Str. 55 D 79106 Freiburg GERMANY Tel +49-761-270-23060 Fax +49-761-270-23960 E-Mail nils.schallner@uniklinik-freiburg.de Freiburg, February 25, 2013 University Medical Center Freiburg Department of Anesthesia and Critical Care Medicine • D 79106 Freiburg Cover Letter Dalton Transactions DOI: 10.1039/c2dt32174b. Author Leo E. Otterbein as a former collaborator of Alfama Lda. no longer has any professional relationship or equity interests in the company. These conflicts of interest do not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials. The remaining authors declare no competing financial interests.

Author Contributions

Conceived and designed the experiments: NS TL UG. Performed the experiments: NS JB UG. Analyzed the data: NS JB UG. Contributed reagents/materials/analysis tools: CR WL LO HB. Wrote the paper: NS CR LO TL UG.