About the Authors

Anita M. Schuwald

Affiliation Department of Pharmacology, Biocenter, Goethe University, Frankfurt, Germany

Michael Nöldner

Affiliation Dr. Willmar Schwabe Pharmaceuticals, Karlsruhe, Germany

Thomas Wilmes

Affiliation Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Albert-Ludwigs Universität, Freiburg, Germany

Norbert Klugbauer

Affiliation Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Albert-Ludwigs Universität, Freiburg, Germany

Kristina Leuner

Leuner@pharmtech.uni-erlangen.de

Affiliation Department of Molecular and Clinical Pharmacy, Friedrich-Alexander University, Erlangen, Germany

Walter E. Müller

Affiliation Department of Pharmacology, Biocenter, Goethe University, Frankfurt, Germany

Competing Interests

The authors have read the journal's policy and have the following conflicts: M. Nöldner is a full time employee of Dr. Willmar Schwabe Pharmaceuticals. K. Leuner received research support by Dr. Willmar Schwabe Pharmaceuticals. W. E. Müller received research support as well as speaker and scientific advisor honorarium by Dr. Willmar Schwabe Pharmaceuticals. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AMS MN TW NK KL WEM. Performed the experiments: AMS MN TW. Analyzed the data: AMS NM TW NK KL WEM. Wrote the paper: AMS KL WEM.