Valproic Acid Inhibits the Release of Soluble CD40L Induced by Non-Nucleoside Reverse Transcriptase Inhibitors in Human Immunodeficiency Virus Infected Individuals

Donna C. Davidson; Giovanni Schifitto; Sanjay B. Maggirwar

doi:10.1371/journal.pone.0059950

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Open Access

Peer-reviewed

Research Article

Valproic Acid Inhibits the Release of Soluble CD40L Induced by Non-Nucleoside Reverse Transcriptase Inhibitors in Human Immunodeficiency Virus Infected Individuals

Donna C. Davidson,

Affiliation Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America
⨯
Giovanni Schifitto,

Affiliation Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America
⨯
Sanjay B. Maggirwar

* E-mail: sanjay_maggirwar@urmc.rochester.edu

Affiliation Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America
⨯

Valproic Acid Inhibits the Release of Soluble CD40L Induced by Non-Nucleoside Reverse Transcriptase Inhibitors in Human Immunodeficiency Virus Infected Individuals

Donna C. Davidson,
Giovanni Schifitto,
Sanjay B. Maggirwar

Published: March 28, 2013
https://doi.org/10.1371/journal.pone.0059950

About the Authors

Donna C. Davidson

Affiliation Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America

Giovanni Schifitto

Affiliation Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America

Sanjay B. Maggirwar

* E-mail: sanjay_maggirwar@urmc.rochester.edu

Affiliation Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DCD GS SBM. Performed the experiments: DCD SBM. Analyzed the data: DCD GS SBM. Contributed reagents/materials/analysis tools: GS SBM. Wrote the paper: DCD SBM.

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Platelet activation
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Platelets
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HIV infections
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Antiretroviral therapy
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Antiretrovirals
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Highly-active antiretroviral therapy
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HIV
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Reverse transcriptase inhibitors
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