About the Authors
- Carlos L. J. Vrins
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* E-mail: c_vrins@hotmail.com
Affiliations Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands, Division of Biopharmaceutics, Leiden/Amsterdam Center for Drug Research, Leiden University, The Netherlands, Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands
- Ruud Out
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Affiliation Division of Biopharmaceutics, Leiden/Amsterdam Center for Drug Research, Leiden University, The Netherlands
- Peter van Santbrink
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Affiliation Division of Biopharmaceutics, Leiden/Amsterdam Center for Drug Research, Leiden University, The Netherlands
- André van der Zee
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Affiliation Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands
- Tokameh Mahmoudi
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Affiliation Department of Biochemistry, Erasmus University Medical Centre, Rotterdam, The Netherlands
- Martine Groenendijk
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Affiliation TNO Prevention and Health, Gaubius Laboratory, Leiden, The Netherlands
- Louis M. Havekes
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Affiliations TNO Prevention and Health, Gaubius Laboratory, Leiden, The Netherlands, Department of General Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands
- Theo J. C. van Berkel
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Affiliation Division of Biopharmaceutics, Leiden/Amsterdam Center for Drug Research, Leiden University, The Netherlands
- Ko Willems van Dijk
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Affiliations Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands, Department of General Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands
- Erik A. L. Biessen
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Affiliations Division of Biopharmaceutics, Leiden/Amsterdam Center for Drug Research, Leiden University, The Netherlands, Department of Pathology, Maastricht University Medical Center, Maastricht, The Netherlands
Competing Interests
The authors have the following interests: Authors Martine Groenendijk and Louis M. Havekes are employed by TNO Prevention and Health. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: CV KWD EB. Performed the experiments: CV RO PS AZ TM MG. Analyzed the data: CV RO TM LH TB KWD EB. Contributed reagents/materials/analysis tools: RO PS AZ TM LH. Wrote the paper: CV KWD EB.