About the Authors

Hana M. Dobrovolny

Affiliations Department of Physics and Astronomy, Texas Christian University, Fort Worth, Texas, United States of America, Department of Physics, Ryerson University, Toronto, Ontario, Canada

Micaela B. Reddy

Affiliation F. Hoffmann-La Roche Inc., Nutley, New Jersey, United States of America

Mohamed A. Kamal

Affiliation F. Hoffmann-La Roche Inc., Nutley, New Jersey, United States of America

Craig R. Rayner

Affiliation Roche Products Pty Ltd. and Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Melbourne, Australia

Catherine A. A. Beauchemin

cbeau@ryerson.ca

Affiliation Department of Physics, Ryerson University, Toronto, Ontario, Canada

Competing Interests

MBR, MAK & CRR are employed by the pharmaceutical company F. Hoffmann-La Roche Ltd. CAAB received a consultancy fee as part of a research contract with F. Hoffmann-La Roche Ltd, while HMD was supported in part by the research contract between CAAB and F. Hoffmann-La Roche Ltd. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: CAAB. Performed the experiments: HMD. Analyzed the data: HMD CAAB. Wrote the paper: HMD MBR MAK CRR CAAB.