About the Authors

Henrik Nausch

Affiliation Department of Agrobiotechnology, Agricultural and Environmental Faculty, University of Rostock, Rostock, Germany

Jana Huckauf

Affiliation Department of Agrobiotechnology, Agricultural and Environmental Faculty, University of Rostock, Rostock, Germany

Roswitha Koslowski

Affiliation Bioserv GmbH, Rostock, Germany

Udo Meyer

Affiliation Bioserv GmbH, Rostock, Germany

Inge Broer

inge.broer@uni-rostock.de

Affiliation Department of Agrobiotechnology, Agricultural and Environmental Faculty, University of Rostock, Rostock, Germany

Heike Mikschofsky

Affiliation Department of Agrobiotechnology, Agricultural and Environmental Faculty, University of Rostock, Rostock, Germany

Competing Interests

The authors have the following interests. Roswitha Koslowski and Udo Meyer are employed by BIOSERV GmbH. The experiments for this publication were done in cooperation BIOSERV GmbH. The company provided the equipment for the Bioassay in order to test the biological activity of plant-made C5a. There are no further patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Gave general technical assistance: JH. Performed the IL6-bioassay: RK. Conceived and designed the experiments: HN UM IB HM. Performed the experiments: HN. Analyzed the data: HN HM. Contributed reagents/materials/analysis tools: UM IB. Wrote the paper: HN IB HM.