About the Authors

Shameka J. Shelby

Affiliation Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

Karen Colwill

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

Sirano Dhe-Paganon

Affiliations Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada, Department of Physiology, University of Toronto, Toronto, Ontario, Canada

Tony Pawson

Affiliations Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada, Department of Medical Genetics, University of Toronto, Toronto, Ontario, Canada

Debra A. Thompson

dathom@umich.edu

Affiliations Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan, United States of America, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

Competing Interests

Funding from GlaxoSmithKline and Merck & Co. was received by, and contributed to, the general operating costs of the Structural Genomics Consortium at the University Toronto. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SJS DAT. Performed the experiments: SJS. Analyzed the data: SJS DAT. Contributed reagents/materials/analysis tools: DAT KC SD TP. Wrote the paper: SJS DAT.