About the Authors

Marina Wayama

Contributed equally to this work with: Marina Wayama, Shuhei Ota

Affiliation Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba, Japan

Shuhei Ota

Contributed equally to this work with: Marina Wayama, Shuhei Ota

Affiliations Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba, Japan, JST-CREST, Kashiwa, Chiba, Japan

Hazuki Matsuura

Affiliation Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba, Japan

Nobuhito Nango

Affiliation Ratoc System Engineering Co., Ltd., Tokyo, Japan

Aiko Hirata

Affiliations Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba, Japan, Bioimaging Center, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba, Japan

Shigeyuki Kawano

kawano@k.u-tokyo.ac.jp

Affiliations Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba, Japan, JST-CREST, Kashiwa, Chiba, Japan

Competing Interests

The fourth author, NN, is affiliated with a commercial company (Ratoc System Engineering Co. Ltd., Tokyo, Japan). In the study described in this paper, the author was responsible for 3D image reconstruction using an application developed by Ratoc System Engineering Co. Ltd. This was a scientific collaboration, and there is no commercial relationship between our laboratory in the the University of Tokyo and Ratoc System Engineering Co. Ltd. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SK. Performed the experiments: MW SO HM AH. Analyzed the data: MW SO. Contributed reagents/materials/analysis tools: NN. Wrote the paper: SO SK.