About the Authors

Hisashi Urushihara

urushihara.hisashi.2s@kyoto-u.ac.jp

Affiliation Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan

Masanori Taketsuna

Affiliation Asia-Pacific Statistical Sciences, Eli Lilly Japan K.K., Kobe, Hyogo, Japan

Ying Liu

Affiliation Global Patient Safety Japan, Eli Lilly Japan K.K., Kobe, Hyogo, Japan

Eisei Oda

Affiliation Medical TOUKEI Corporation, Shinjuku-ku, Tokyo, Japan

Masaki Nakamura

Affiliation Business Development Department, Medical Data Vision Co., Ltd., Chiyoda-ku, Tokyo, Japan

Shinichi Nishiuma

Affiliation Global Patient Safety Japan, Eli Lilly Japan K.K., Kobe, Hyogo, Japan

Rei Maeda

Affiliation Global Patient Safety Japan, Eli Lilly Japan K.K., Kobe, Hyogo, Japan

Competing Interests

HU has served as a consultant to Eli Lilly Japan and received a research grant from Pfizer Health Research Foundation. MT, YL, SN, and RM are full-time employees of Eli Lilly Japan. EO is the President of Medical TOUKEI Corporation. MN is a full-time employee of Medical Data Vision Co., Ltd. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: HU MT YL EO SN RM. Analyzed the data: EO MN. Wrote the paper: HU. Acquisition of data: MN. Interpreted the data: HU MT YL EO MN SN RM. Critical revision of the manuscript for important intellectual content: HU MT YL SN RM.