About the Authors

Alicia P. Higueruelo, Adrian Schreyer, G. Richard J Bickerton, Tom L. Blundell, Will R. Pitt
Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

Will R. Pitt
UCB Pharma, Slough, United Kingdom

Corresponding Author

alicia@cryst.bioc.cam.ac.uk

Competing Interests

WRP is an employee of UCB Pharma. However, the work was carried out while he was seconded to the University of Cambridge and he has no competing interests in the material in this manuscript. Therefore this does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials. The authors have declared that no other competing interests exist.

Author Contributions

Conceived and designed the experiments: APH TLB WRP. Performed the experiments: APH. Analyzed the data: APH. Contributed reagents/materials/analysis tools: AS GRJB. Wrote the paper: APH TLB WRP. Reviewed and edited the final version of the manuscript: APH AS GRJB TLB WRP.