About the Authors

Rahman Md. Mostafeezur

Contributed equally to this work with: Rahman Md. Mostafeezur, Hossain Md. Zakir

Affiliation Division of Oral Physiology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

Hossain Md. Zakir

Contributed equally to this work with: Rahman Md. Mostafeezur, Hossain Md. Zakir

Affiliation Division of Oral Physiology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

Hanako Takatsuji

Affiliation Division of Oral Physiology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

Yoshiaki Yamada

Affiliation Division of Oral Physiology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

Kensuke Yamamura

Affiliation Division of Oral Physiology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

Junichi Kitagawa

kitagawa@dent.niigata-u.ac.jp

Affiliation Division of Oral Physiology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

Competing Interests

The authors have read the journal’s policy and have the following conflicts: the work was partly supported by a grant from Ono Pharmaceutical Co., Ltd. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: HMZ RMM HT JK. Performed the experiments: HMZ RMM HT JK. Analyzed the data: HMZ RMM YY KY JK. Wrote the paper: HMZ RMM JK.