About the Authors

Liis Uusküla, Jaana Männik, Kristiina Rull, Maris Laan
Human Molecular Genetics Group, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia

Jaana Männik
Department of Biochemistry, Cellular and Molecular Biology, University of Tennessee, Knoxville, Tennessee, United States of America

Kristiina Rull, Pille Vaas, Pille Teesalu
Department of Obstetrics and Gynecology, Tartu University Hospital, Tartu, Estonia

Ave Minajeva
Department of Pathology, Tartu University Hospital, Tartu, Estonia

Sulev Kõks
Department of Physiology, Center of Translational Medicine, University of Tartu, Tartu, Estonia

Jüri Reimand
Donnelly Centre, University of Toronto, Toronto, Ontario, Canada

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ML LU JR KR JM. Performed the experiments: LU KR JM AM. Analyzed the data: JR SK LU JM. Contributed reagents/materials/analysis tools: ML JR. Wrote the paper: LU ML JR JM. Large-scle bioinformatic data analysis: JR. Recruitment of the study participants and collection of clinical information: PV PT KR. Collection and management of the biological samples of the study: PV PT KR ML JM. Interpretation of the study data: ML LU JM JR KR AM. Critical reading and commenting of the manuscript: KR AM SK PV. Approval of the final manuscript: LU JM KR AM SK PV PT JR ML.