About the Authors

Tomonori Takami

Affiliations Division of Molecular Pharmacology and Pharmacogenomics, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Japan, Chemical Analysis Section, JCL Bioassay Corporation, Nishiwaki, Japan

Yue Fang

fangyue@mail.cmu.edu.cn

Affiliations Division of Molecular Pharmacology and Pharmacogenomics, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Japan, Department of Pharmacology, School of Pharmaceutical Sciences, China Medical University, Shenyang, China

Xin Zhou

Affiliations Division of Molecular Pharmacology and Pharmacogenomics, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Japan, The First Affiliated Hospital of Liaoning Medical University, Jinzhou, China

Wurentuya Jaiseng

Affiliation Division of Molecular Pharmacology and Pharmacogenomics, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Japan

Yan Ma

Affiliation Division of Molecular Pharmacology and Pharmacogenomics, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Japan

Takayoshi Kuno

Affiliations Division of Molecular Pharmacology and Pharmacogenomics, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Japan, Department of Pharmacology, School of Pharmaceutical Sciences, China Medical University, Shenyang, China

Competing Interests

Tomonori Takami is employed by the commercial company JCL Bioassay Corporation. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: YF TK TT. Performed the experiments: TT YF XZ WJ YM. Analyzed the data: TT YF XZ WJ YM TK. Contributed reagents/materials/analysis tools: YF YM TK. Wrote the paper: YF TT TK.