About the Authors

Eric A. Tanifum

Affiliations Pediatric Radiology, Texas Children’s Hospital, Houston, Texas, United States of America, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Indrani Dasgupta

Current address: Department of Anatomy & Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Affiliation School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Mayank Srivastava

Affiliations Pediatric Radiology, Texas Children’s Hospital, Houston, Texas, United States of America, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Rohan C. Bhavane

Affiliations Pediatric Radiology, Texas Children’s Hospital, Houston, Texas, United States of America, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Li Sun

Affiliation Department of Pharmacology and Pharmaceutical Sciences, University of Houston, Houston, Texas, United States of America

John Berridge

Affiliation Department of Pharmacology and Pharmaceutical Sciences, University of Houston, Houston, Texas, United States of America

Hoda Pourgarzham

Affiliation Department of Pharmacology and Pharmaceutical Sciences, University of Houston, Houston, Texas, United States of America

Rashmi Kamath

Affiliation Pediatric Radiology, Texas Children’s Hospital, Houston, Texas, United States of America

Gabriela Espinosa

Affiliation Pediatric Radiology, Texas Children’s Hospital, Houston, Texas, United States of America

Stephen C. Cook

Affiliation Fieldstone Partners, Houston, Texas, United States of America

Jason L. Eriksen

jeriksen@central.uh.edu (JLE); avannapr@texaschildrens.org (AA)

Affiliation School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Ananth Annapragada

jeriksen@central.uh.edu (JLE); avannapr@texaschildrens.org (AA)

Affiliations Pediatric Radiology, Texas Children’s Hospital, Houston, Texas, United States of America, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America, Department of Radiology, Baylor College of Medicine, Houston, Texas, United States of America

Competing Interests

AA, JLE, SCC, EAT, ID and MS own stock in Alzeca Biosciences LLC. SCC is employed by Fieldstone Partners, a venture firm that also holds stock in Alzeca Biosciences LLC. Alzeca has no products at this time, but seeks to develop imaging agents for Alzheimers Disease diagnosis and tracking. Alzeca has licensed technology co-developed by the authors of this paper, but no patents have issued yet. This does not alter the authors’ adherence to all the PLOS ONE policies of sharing data and materials.

Author Contributions

Conceived and designed the experiments: EAT ID MS SCC JLE AA. Performed the experiments: EAT ID MS RCB LS JB HP RK GE JLE. Analyzed the data: EAT ID MS JLE AA. Contributed reagents/materials/analysis tools: JLE AA. Wrote the paper: EAT ID MS JLE AA.