About the Authors

Ali Nsair

Contributed equally to this work with: Ali Nsair, Katja Schenke-Layland

ansair@mednet.ucla.edu

Affiliations Department of Medicine and Physiology, Cardiovascular Research Laboratory, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America, The Edythe and Eli Broad Center for Regenerative Medicine and Stem Cell Research, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

Katja Schenke-Layland

Contributed equally to this work with: Ali Nsair, Katja Schenke-Layland

Affiliations Department of Medicine and Physiology, Cardiovascular Research Laboratory, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America, Department of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart, Germany, Department of Thoracic and Cardiovascular Surgery, Eberhard Karls University, Tübingen, Germany

Ben Van Handel

Affiliations Department of Molecular, Cell and Developmental Biology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America, The Edythe and Eli Broad Center for Regenerative Medicine and Stem Cell Research, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

Denis Evseenko

Affiliations Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America, The Edythe and Eli Broad Center for Regenerative Medicine and Stem Cell Research, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

Michael Kahn

Affiliation Department of Biochemistry and Molecular Biology and Institute for Stem Cell and Regenerative Medicine, University of Southern California, Los Angeles, California, United States of America

Peng Zhao

Affiliation Department of Medicine and Physiology, Cardiovascular Research Laboratory, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

Joseph Mendelis

Affiliation Department of Medicine and Physiology, Cardiovascular Research Laboratory, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

Sanaz Heydarkhan

Address Current address: Department of Medicine and Physiology, Cardiovascular Research Laboratory, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

Affiliation Department of Medicine and Physiology, Cardiovascular Research Laboratory, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

Obina Awaji

Address Current address: Department of Medicine and Physiology, Cardiovascular Research Laboratory, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

Affiliation Department of Medicine and Physiology, Cardiovascular Research Laboratory, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

Miriam Vottler

Affiliations Department of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart, Germany, Department of Thoracic and Cardiovascular Surgery, Eberhard Karls University, Tübingen, Germany

Susanne Geist

Affiliations Department of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart, Germany, Department of Thoracic and Cardiovascular Surgery, Eberhard Karls University, Tübingen, Germany

Jennifer Chyu

Affiliation Department of Medicine and Physiology, Cardiovascular Research Laboratory, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

Nuria Gago-Lopez

Affiliation Department of Medicine and Physiology, Cardiovascular Research Laboratory, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

Gay M. Crooks

Affiliations Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America, The Edythe and Eli Broad Center for Regenerative Medicine and Stem Cell Research, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

Kathrin Plath

Affiliation The Edythe and Eli Broad Center for Regenerative Medicine and Stem Cell Research, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

Josh Goldhaber

Affiliation Cedars-Sinai Heart Institute, Los Angeles, California, United States of America

Hanna K. A. Mikkola

Affiliations Department of Molecular, Cell and Developmental Biology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America, The Edythe and Eli Broad Center for Regenerative Medicine and Stem Cell Research, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

W. Robb MacLellan

Affiliation Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, Washington, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AN KSL BVH HKAM KP GMC WRM. Performed the experiments: AN KSL BVH PZ NGL JC MV SG SH OA. Analyzed the data: AN KSL BVH DE MK PZ JM NGL GMC JG HKAM WRM. Wrote the paper: AN KSL BVH HKAM WRM.