About the Authors

Sian E. Piret

Contributed equally to this work with: Sian E. Piret, Christopher T. Esapa

Affiliation Nuffield Department of Clinical Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom

Christopher T. Esapa

Contributed equally to this work with: Sian E. Piret, Christopher T. Esapa

Affiliations Nuffield Department of Clinical Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom, Mammalian Genetics Unit, MRC Harwell, Harwell Science and Innovation Campus, United Kingdom

Caroline M. Gorvin

Affiliation Nuffield Department of Clinical Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom

Rosie Head

Affiliations Nuffield Department of Clinical Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom, Mammalian Genetics Unit, MRC Harwell, Harwell Science and Innovation Campus, United Kingdom

Nellie Y. Loh

Affiliation Nuffield Department of Clinical Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom

Olivier Devuyst

Affiliation Institute of Physiology, Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland

Gethin Thomas

Affiliation The University of Queensland Diamantina Institute, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia

Steve D. M. Brown

Affiliation Mammalian Genetics Unit, MRC Harwell, Harwell Science and Innovation Campus, United Kingdom

Matthew Brown

Affiliations Nuffield Department of Clinical Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom, The University of Queensland Diamantina Institute, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia

Peter Croucher

Affiliation Garvan Institute for Medical Research, Sydney, Australia

Roger Cox

Affiliation Mammalian Genetics Unit, MRC Harwell, Harwell Science and Innovation Campus, United Kingdom

Rajesh V. Thakker

rajesh.thakker@ndm.ox.ac.uk

Affiliation Nuffield Department of Clinical Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SEP CTE OD GT SDMB MB RC RVT. Performed the experiments: SEP CTE CMG RH NYL PC. Analyzed the data: SEP CTE NYL OD PC RVT. Wrote the paper: SEP CTE CMG RH NYL OD GT SDMB MB PC RC RVT.