About the Authors

Iain Rogers

Contributed equally to this work with: Iain Rogers, Fiona Kerr

Affiliation Institute of Healthy Ageing and GEE, University College London, London, United Kingdom

Fiona Kerr

Contributed equally to this work with: Iain Rogers, Fiona Kerr

Affiliation Institute of Healthy Ageing and GEE, University College London, London, United Kingdom

Pedro Martinez

Affiliation Institute of Healthy Ageing and GEE, University College London, London, United Kingdom

John Hardy

Affiliation Institute of Neurology, University College London, London, United Kingdom

Simon Lovestone

Affiliation MRC Centre for Neurodegeneration Research, Institute of Psychiatry, King's College London, London, United Kingdom

Linda Partridge

l.partridge@ucl.ac.uk (LP)

Affiliations Institute of Healthy Ageing and GEE, University College London, London, United Kingdom, Max Planck Institute for Biology of Ageing, Köln, Germany

Competing Interests

The authors have received funding from a commercial source, Eisai London Research Laboratories (UK). This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: IR FK JH SL LP. Performed the experiments: IR FK PM. Analyzed the data: IR FK. Contributed reagents/materials/analysis tools: IR FK PM. Wrote the paper: IR FK JH SL LP.