About the Authors

Anna P. Pilbrow

E-mail: anna.pilbrow@otago.ac.nz

Affiliation Christchurch Cardioendocrine Research Group, Department of Medicine, University of Otago Christchurch, Christchurch, New Zealand

Lasse Folkersen

Affiliation Department of Medicine, Karolinska Institutet, Stockholm, Sweden

John F. Pearson

Affiliation Department of Public Health and General Practice, University of Otago Christchurch, Christchurch, New Zealand

Chris M. Brown

Affiliation Department of Biochemistry, University of Otago, Dunedin, New Zealand

Les McNoe

Affiliation Department of Biochemistry, University of Otago, Dunedin, New Zealand

Nancy M. Wang

Affiliations Christchurch Cardioendocrine Research Group, Department of Medicine, University of Otago Christchurch, Christchurch, New Zealand, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, Department of Public Health and General Practice, University of Otago Christchurch, Christchurch, New Zealand, Department of Biochemistry, University of Otago, Dunedin, New Zealand, Department of Cardiovascular Medicine, Kaufman Center for Heart Failure, Cleveland Clinic, Cleveland, Ohio, United States of America, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

Wendy E. Sweet

Affiliation Department of Cardiovascular Medicine, Kaufman Center for Heart Failure, Cleveland Clinic, Cleveland, Ohio, United States of America

W. H. Wilson Tang

Affiliation Department of Cardiovascular Medicine, Kaufman Center for Heart Failure, Cleveland Clinic, Cleveland, Ohio, United States of America

Michael A. Black

Affiliation Department of Biochemistry, University of Otago, Dunedin, New Zealand

Richard W. Troughton

Affiliation Christchurch Cardioendocrine Research Group, Department of Medicine, University of Otago Christchurch, Christchurch, New Zealand

A. Mark Richards

Affiliation Christchurch Cardioendocrine Research Group, Department of Medicine, University of Otago Christchurch, Christchurch, New Zealand

Anders Franco-Cereceda

Affiliation Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

Anders Gabrielsen

Affiliation Department of Medicine, Karolinska Institutet, Stockholm, Sweden

Per Eriksson

Affiliation Department of Medicine, Karolinska Institutet, Stockholm, Sweden

Christine S. Moravec

Affiliation Department of Cardiovascular Medicine, Kaufman Center for Heart Failure, Cleveland Clinic, Cleveland, Ohio, United States of America

Vicky A. Cameron

Affiliation Christchurch Cardioendocrine Research Group, Department of Medicine, University of Otago Christchurch, Christchurch, New Zealand

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: VAC APP RWT CSM WHWT. Performed the experiments: WES APP LM. Analyzed the data: JFP CMB MAB APP. Wrote the paper: APP. Conceived the study: VAC APP RWT CSM WHWT. Provided donor heart tissue for the study: CSM WES. Prepared the heart donor tissue, RNA and DNA samples: WES APP. Performed the array experiments: LM. Provided gene expression and genotyping data for aorta, mammary artery and carotid plaque tissues: LF AFC AG PE. Performed the genotyping and wrote the first draft of the manuscript: APP. Performed the RT-qPCR analysis of the donor hearts: APP NMW. Performed statistical and bioinformatic analysis: APP JFP CMB MAB APP. Provided clinical input: WHWT RWT AMR. Contributed to the interpretation of the data and revision of the manuscript: APP LF JFP CMB LM NMW WES WHWT MAB RWT AMR AFC AG PE CSM VAC. Obtained funding for the study: APP VAC RWT AMR CSM AG PE.